Chinese Journal of Tissue Engineering Research ›› 2014, Vol. 18 ›› Issue (52): 8487-8490.doi: 10.3969/j.issn.2095-4344.2014.52.022

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Biodynamic properties of vascular anastomosis using a new-type degradable anastomosis clip

Zhang Qiong, Xu Shuo-gui   

  1. Changhai Hospital, Second Military Medical University of PLA, Shanghai 200433, China
  • Revised:2014-10-03 Online:2014-12-17 Published:2014-12-17
  • Contact: Xu Shuo-gui, Associate professor, Changhai Hospital, Second Military Medical University of PLA, Shanghai 200433, China
  • About author:Zhang Qiong, Changhai Hospital, Second Military Medical University of PLA, Shanghai 200433, China

Abstract:

BACKGROUND: vailable anastomats appear to overcome the deficiencies of traditional anastomotic methods, such as complex operation, long time for vascular anastomosis and severe intimal injury. However, their nonabsorbable needling rings impact the normal diastolic and systolic of the blood vessels at anastomotic sites, thus limiting the growth of blood vessels, which is not suitable for minor patients.

OBJECTIVE: To analyze the biomechanical characteristics of vascular anastomosis with a new-type degradable anastomosis chip.
METHODS: Bilateral jugular veins of New Zealand rabbits were cut: one side was anastomosed using a new type degradable anastomosis chip, and the other side was anastomosed with sutures as control. The average maximal breaking pressure was measured at the 1st day, 7th day, 14th day, and 30th day after operation.
RESULTS AND CONCLUSION: The anastomosis time using the anastomosis chip was lower than that using sutures (P < 0.05), and the average maximal breaking pressure exhibited no difference between the two groups (P < 0.05). It indicates that the new-type degradable anastomosis chip is safe and reliable.

中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程


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Key words:  biocompatible materials, absorbable implants, biomechanics

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